KIDNEY INJURY MOLECULE-1 EXPRESSION PREDICTS STRUCTURAL DAMAGE AND OUTCOME IN HISTOLOGICAL ACUTE TUBULAR INJURY

Kidney injury molecule-1 expression predicts structural damage and outcome in histological acute tubular injury

Background: A few studies have shown that urinary kidney injury molecule-1 (uKIM-1) levels are increased in acute kidney injury (AKI); however, the correlation between uKIM-1 and histological tubular injury, which is considered to obermeyer perseus bib pants be the gold standard for evaluating renal damage and predicting prognosis, is still unclear

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Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors.Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored.Extracellular vesicles have been implicated as criti

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